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Please use this identifier to cite or link to this item: http://hdl.handle.net/10348/1747

Title: Tartrate-resistant acid phosphatase as a biomarker of bone turnover in dog
Authors: Sousa, C.P.
Nery, F.
Azevedo, Jorge Manuel Teixeira de
Viegas, Carlos A.
Gomes, M.E.
Dias, Maria Isabel R.
Issue Date: 2011
Abstract: Values of serum tartrate-resistant acid phosphatase (TRAP)activity were obtained in adult dogs and its biological variability was assessed. Nine healthy skeletally mature Portuguese Podengo dogs were used for the determination of TRAP, total and bone alkaline phosphatase serum activities, and also to styudy their relashionship with serum minerals, namely calcium (Ca) phosphorous (P),and magnesium (Mg).The serum TRAP activity was 2.19+-0.56IU/mL,with intra-individual variation of 18,3% and inter-individual variation of 25.6%. Significant correlations were observed between serum TRAP activity and Ca(r=0.3431;P < 0.05),Ca and Mg(r=0.787;P<0.01), and TRAP and MG(r=0.397;P<0,05). The results indicate that serum TRAP activity in dog could be of great value in research and in clinical practice,providing complementary non-invasive information on bone metabolism.
Keywords: cão
metabolismo ósseo
reabsorção
osteoclaste
URI: http://hdl.handle.net/10348/1747
Appears in Collections:OLD - DZOO - Resumo de Comunicação em Conferência Internacional

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